1. Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats: ” Olive leaf extract is associated with improved glucose homeostasis in humans. Animal models indicate that this may be facilitated through the reduction of starch digestion and absorption. Olive leaf extract may represent an effective adjunct therapy that normalizes glucose homeostasis in individuals with diabetes.” http://www.ncbi.nlm.nih.gov/pubmed/22512698
2. Antidiabetic effect of Olea europaea: “A comparison was made between the action of olive leaves extract and glibenclamide (600 microg/kg), a known antidiabetic drug. The antidiabetic effect of the extract was more effective than that observed with glibenclamide.” http://www.ncbi.nlm.nih.gov/pubmed/18844257
3. Olive (Olea europaea L.) leaf extract attenuates early diabetic neuropathic pain through prevention of high glucose-induced apoptosis: in vitro and in vivo studies: “The results suggest that olive leaf extract inhibits high glucose-induced neural damage and suppresses diabetes-induced thermal hyperalgesia. The mechanisms of these effects may be due, at least in part, to reduce neuronal apoptosis and suggest therapeutic potential of oliveleaf extract in attenuation of diabetic neuropathic pain.” http://www.ncbi.nlm.nih.gov/pubmed/21540099
4. Study Finds Olive Leaf Extract Useful in Diabetes Management.
5. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial: “Supplementation with olive leaf polyphenols for 12 weeks significantly improved insulin sensitivity and pancreatic β-cell secretory capacity in overweight middle-aged men at risk of developing the metabolic syndrome.” http://www.ncbi.nlm.nih.gov/pubmed/23516412
6. Dried leaf extract of Olea europaea ameliorates islet-directed (Diabetic) autoimmunity…: “The health-promoting effects of various constituents of the olive tree (Olea europaea) are mainly associated with hypoglycaemic and insulin-sensitising activities and have been widely demonstrated in the metabolic syndrome and type 2 diabetes… The results suggest that DOLE (Dried Olive Leaf Extract) interferes with development of autoimmune diabetes by down-regulating production of proinflammatory and cytotoxic mediators. Therefore, the potential use of a DOLE ((Dried Olive Leaf Extract)-enriched diet for prophylaxis/treatment of human T1D (Type 1 Diabetes), and possibly other autoimmune diseases, is worthy of further investigation. http://www.ncbi.nlm.nih.gov/pubmed/20025835