My Olive Leaf

Results Speak Louder Than Words

High Blood Pressure

Olive Leaf and High Blood Pressure:

1. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension comparison with Captopril: “In conclusion, Olive (Olea europaea) leaf extract, at the dosage regimen of 500 mg twice daily, was similarly effective in lowering systolic and diastolic blood pressures in subjects with stage-1 hypertension as Captopril, given at its effective dose of 12.5-25 mg twice daily.” http://www.ncbi.nlm.nih.gov/pubmed/21036583

2. A clinical trial of a titrated Olea extract in the treatment of essential arterial hypertension:  “We note for all patients a statistically significant decrease of blood pressure.” http://www.ncbi.nlm.nih.gov/pubmed/8786521

3. Blood pressure lowering effect of an olive leaf extract (Olea europaea)… “The findings confirm previous reports on the hypotensive (lowering of blood pressure) effects of olive leaf.” http://www.ncbi.nlm.nih.gov/pubmed/12489249

4. Food supplementation with an olive (Olea europaea L.) leaf extract reduces blood pressure in borderline hypertensive monozygotic twins: “Concluding, the study confirmed the antihypertensive and cholesterol-lowering action of EFLA943 (olive leaf extract) in humans.” http://www.ncbi.nlm.nih.gov/pubmed/18729245

5. Olive Leaf Safely Modulates Blood Pressure: http://www.lifeextension.com/magazine/2012/3/olive-leaf-safely-modulates-blood-pressure/page-01

6. Antithrombotic effect of repeated doses of the ethanolic extract of local olive (Olea europaea L.) leaves: “The incidence of thromboembolic diseases is increasing, and they are a major cause of mortality and morbidity worldwide. Mediterranean diet is known for its high content of olive products, especially olive oil, which has known cardiovascular health benefits, including those on blood pressure, cholesterol level, and thrombogenesis. All previous animal and clinical studies investigating the beneficial antithrombotic effects of olives have focused on olive oil and a few on olive leaves (OLEs). In this study, the ethanolic extract of OLE was evaluated for its antithrombotic activity in the rabbit model of thrombosis induced by ligature of the vena cava and intravenous administration of tissue thromboplastin… One important finding in this study concerns thrombus morphology. In the extract treatment groups, the thrombus was filament-like and did not adhere to blood vessel walls, whereas in the control group the thrombus was thick and almost completely occluded the vein. Therefore, these results suggest that OLE (Olive Leaf Extract) ethanolic extract can modify the extrinsic coagulation pathway as evidenced by the prolongation of PT and changes in thrombus morphology.” http://www.ncbi.nlm.nih.gov/pubmed/23702352

7. The effects of polyphenols in olive leaves on platelet function: “The phenolic compounds of olive leaves and olive oils in the Mediterranean diet have been associated with a reduced incidence of heart disease. Accordingly, antioxidant-rich diets may prevent the deleterious effects of oxidative metabolism by scavenging free radicals, thus inhibiting oxidation and delaying atherosclerosis… Olive leaf polyphenols derived from O. europaea L. leaves inhibited in vitro platelet activation in healthy, non-smoking males.” http://www.ncbi.nlm.nih.gov/pubmed/17346951

8. Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves: “All three isolates, in a dose 60 mg/kg b.w. for 6 weeks treatment, prevented the development of severe hypertension and atherosclerosis and improved the insulin resistance of the experimental animals. GO, OA and CT isolates could provide an effective and cheap treatment of this particular, most common type of salt-sensitive hypertension in the African population.” http://www.ncbi.nlm.nih.gov/pubmed/12648829